منابع مشابه
The efficacy of ascorbate treatment after severe experimental alkali burns depends upon the route of administration.
Rabbit eyes were subjected to severe alkali burns (35 sec, 12 mm, 1N sodium hydroxide). In one experiment, rabbits in the treated group received a daily subcutaneous injection of neutralized ascorbic acid solution (0.5 gm/kg body weight), while control animals received no treatment. At the termination of the experiment (30 days), 11 of 16 eyes (68.8%) in the control group had ulcerated or forme...
متن کاملTopical ascorbate decreases the incidence of corneal ulceration after experimental alkali burns.
A double-masked study of the effects of topical ascorbate on alkali burns utilized 37 rabbit eyes subjected to 20 sec, 12 mm, IN sodium hydroxide burns. Preliminary studies established the ocular acceptability, penetrability, and stability of the solutions used. Eighteen eyes in the experimental group were given two drops of10% ascorbate in Adsorbotear vehicle hourly for 14 hr of each day. Nine...
متن کاملChemical burns to the eye.
SIR, Mr S J Morgan emphasises the need to distinguish between ammonia and antipersonnel or antirape sprays such as CS and Mace.' From personal experience over the past 18 months I can describe a very simple and rapid method of differentiation. In a series of 17 patients who had been assaulted with a pungent fluid one had a strong smell of ammonia on his clothes and clinically had features of a ...
متن کاملEffects of topical 10% ascorbate solution on established corneal ulcers after severe alkali burns.
When established corneal ulcers induced by alkali burning were treated with 10% ascorbate drops, no perforation occurred, in contrast to a 25% incidence in the control group. If perforations and descemetoceles were grouped together, these difference became insignificant (i.e., 14.2% ascorbate-treated vs. 25% control). Prolongation of descemetocele presence without perforation in the ascorbate-t...
متن کاملCitrate or ascorbate/citrate treatment of established corneal ulcers in the alkali-injured rabbit eye.
Immediate treatment of alkali-injured eyes with citrate or ascorbate has previously been shown to prevent corneal ulceration and perforation in the rabbit. Other experiments showed that while ascorbate treatment of established ulcers did not appear to lead to significant healing it did reduce perforations by prolonging the presence of descemetoceles. In the present experiment with established u...
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ژورنال
عنوان ژورنال: Emergency Medicine Journal
سال: 2003
ISSN: 1472-0205,1472-0213
DOI: 10.1136/emj.20.5.465